The Annals of thoracic surgery
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Tracheobronchial injuries are rare but potentially life threatening. Their successful diagnosis and treatment often require a high level of suspicion and surgical repairs unique to the given injury. ⋯ A high level of suspicion and the liberal use of bronchoscopy are important in the diagnosis of tracheobronchial injury. A tailored surgical approach is often necessary for definitive repair.
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Randomized Controlled Trial Clinical Trial
Influence of high- and low-dose aprotinin on activation of hemostasis in open heart operations.
The protease inhibitor aprotinin reduces hemostatic activation and blood loss after cardiac operations. The aim of the present study was to investigate the influence of two different aprotinin doses on hemostatic activation and to identify the most effective dose to reduce the postoperative bleeding tendency. ⋯ A high-dose aprotinin regimen was significantly more effective than a low-dose regimen in attenuating fibrinolysis and reducing the bleeding tendency and allogeneic blood requirements, but not in reducing F(1+2) prothrombin fragments. High-dose aprotinin therapy appears to be superior to low-dose therapy.
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A recent study found that a higher-perfusate hematocrit was associated with improved neurologic recovery after deep hypothermic circulatory arrest. The current study examined the relative contributions of oxygen delivery and colloid oncotic pressure to this result, as well as the efficacy of different colloidal agents and modified ultrafiltration. ⋯ Both higher hematocrit and higher colloid oncotic pressure with pentafraction improve cerebral recovery after deep hypothermic circulatory arrest. The higher hematocrit improves cerebral oxygen delivery but does not reduce total body edema. Modified ultrafiltration after cardiopulmonary bypass is less effective than having a higher initial prime hematocrit or colloid oncotic pressure.
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The minimally invasive limited lower sternotomy is a surgical approach for mitral valve operations with easy access to the left atrium. It confers the advantages of preservation of the sternocostal articulations and both internal thoracic arteries, with no need to enter either pleural cavity or resect the costal cartilages. It facilitates aortic and atrial cannulation for cardiopulmonary bypass, and allows easy access to the mitral valve through the left atrium.
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A technique for aortic valve replacement is described in which the aortic valve is exposed through a partial sternotomy without transecting ("T'ing" off) the sternum. Aortic valve replacement can be performed with standard aortic and right atrial cannulation.