Headache
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To perform a prospective epidemiological study of headache in a rural community in Oman, assessing prevalence, symptom profile, and health care utilization pattern. ⋯ This prospective study shows that headache is also highly prevalent in this community. Migraine and tension-type headache have the same prevalence, but the sex distribution for migraine is different from that observed in the Western world. Tension-type headache prevalence was substantially lower than that observed in other parts of the world. Frequent headaches were as common as in other population-based studies worldwide. Analgesic use/overuse probably also coexisted with headache, because self-medication was quite common.
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Randomized Controlled Trial Comparative Study Clinical Trial
Migraine with aura versus migraine without aura: pain intensity and associated symptom intensities after placebo.
To compare the intensity of pain and associated symptoms after placebo administration in patients with migraine with aura and migraine without aura. ⋯ Our findings suggest that studies comparing placebo against an active drug should use stratification according to the presence versus absence of aura.
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Randomized Controlled Trial Comparative Study Clinical Trial
Intravenous dipyrone in the acute treatment of migraine without aura and migraine with aura: a randomized, double blind, placebo controlled study.
Dipyrone (Metamizol) has been used in the acute treatment of migraines in Brazil. Some investigators have found it to be a highly effective medication for migraine pain and associated symptoms. ⋯ Dipyrone is an effective drug for the relief of acute migraine pain and associated symptoms.
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To review psychiatric issues that accompany migraine and means of addressing these issues. ⋯ Migraine is often comorbid with psychiatric disorders, particularly depression and anxiety. The relationship is likely based on shared mechanisms and successful treatment is possible.
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Randomized Controlled Trial Clinical Trial
Children's ibuprofen suspension for the acute treatment of pediatric migraine.
To compare the efficacy of a single over-the-counter dose (7.5 mg/kg, p.o.) of children's ibuprofen suspension vs. placebo for the acute treatment of pediatric migraine. ⋯ Children's ibuprofen suspension at an OTC dose of 7.5 mg/kg is an effective and well-tolerated agent for pain relief in the acute treatment of childhood migraine, particularly in boys. There is a striking difference in gender response rates and placebo responder rates between girls and boys. The boys responded at a statistically significant rate, and girls failed to do so because of a very high placebo responder rate. Multi-center trials are recommended.