Lancet
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Review Meta Analysis
Diagnostic value of clinical features at presentation to identify serious infection in children in developed countries: a systematic review.
Our aim was to identify which clinical features have value in confirming or excluding the possibility of serious infection in children presenting to ambulatory care settings in developed countries. ⋯ Health Technology Assessment and National Institute for Health Research National School for Primary Care Research.
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Randomized Controlled Trial Multicenter Study
Apixaban versus enoxaparin for thromboprophylaxis after knee replacement (ADVANCE-2): a randomised double-blind trial.
Low-molecular-weight heparins such as enoxaparin are preferred for prevention of venous thromboembolism after major joint replacement. Apixaban, an orally active factor Xa inhibitor, might be as effective, have lower bleeding risk, and be easier to use than is enoxaparin. We assessed efficacy and safety of these drugs after elective total knee replacement. ⋯ Bristol-Myers Squibb; Pfizer.