Lancet
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Randomized Controlled Trial Multicenter Study
Efficacy of paracetamol for acute low-back pain: a double-blind, randomised controlled trial.
Regular paracetamol is the recommended first-line analgesic for acute low-back pain; however, no high-quality evidence supports this recommendation. We aimed to assess the efficacy of paracetamol taken regularly or as-needed to improve time to recovery from pain, compared with placebo, in patients with low-back pain. ⋯ National Health and Medical Research Council of Australia and GlaxoSmithKline Australia.