Lancet
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Observational Study
Gestational weight change in a diverse pregnancy cohort and mortality over 50 years: a prospective observational cohort study.
High weight gain in pregnancy is associated with greater postpartum weight retention, yet long-term implications remain unknown. We aimed to assess whether gestational weight change was associated with mortality more than 50 years later. ⋯ National Institutes of Health.
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Randomized Controlled Trial Multicenter Study
Atezolizumab plus bevacizumab versus active surveillance in patients with resected or ablated high-risk hepatocellular carcinoma (IMbrave050): a randomised, open-label, multicentre, phase 3 trial.
No adjuvant treatment has been established for patients who remain at high risk for hepatocellular carcinoma recurrence after curative-intent resection or ablation. We aimed to assess the efficacy of adjuvant atezolizumab plus bevacizumab versus active surveillance in patients with high-risk hepatocellular carcinoma. ⋯ F Hoffmann-La Roche/Genentech.