Lancet
-
Randomized Controlled Trial Clinical Trial
Failure of targeted mass treatment to control schistosomiasis.
An attempt was made to control schistosomiasis mansoni with mass treatment of all subjects excreting more than 100 eggs/g of faeces. No other means of control to reduce transmission were used. ⋯ However, reappearance of eggs, probably indicating reinfection, was very rapid. One year after treatment the egg counts were at about two-thirds of the original level again.
-
Randomized Controlled Trial Clinical Trial
The Australian therapeutic trial in mild hypertension. Report by the Management Committee.
-
Randomized Controlled Trial Comparative Study Clinical Trial
Cryoanalgesia for post-thoracotomy pain.
Intercostal block by a freezing technique was compared with blockade by local anaesthetics or no blockade as a method of treating post-thoracotomy pain. The 15 patients who received cryotherapy had significantly less postoperative pain than the 9 patients whose nerves were blocked by local anaesthetics or who did not receive any nerve block. The interruption of nerve function produced by cryotherapy was temporary (not more than 30 days), and there were no adverse sequelae.
-
Letter Randomized Controlled Trial Clinical Trial
Faecal fat losses and cow's milk lactose.
-
Randomized Controlled Trial Comparative Study Clinical Trial
Combined use of guar and acarbose in reduction of postprandial glycaemia.
Symptoms associated with carbohydrate malabsorption limit the usefulness to diabetics of a powerful glycoside-hydrolase inhibitor (acarbose) which reduces postprandial glycaemia. Addition of a low dose (50 mg) of a acarbose together with 14.5 g guar gum to a breakfast test meal taken by 8 healthy volunteers reduced the mean peak rise in blood-glucose at 30 min by 70%. ⋯ When acarbose was taken alone, 3 of the 8 subjects had troublesome symptoms and the 30 min rise in blood-glucose was reduced by only 28%. Thus, combination of these two agents effectively reduces the rate of carbohydrate absorption without increasing side-effects and may make combined acarbose and guar acceptable in the management of some diabetics.