Medicine
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The coexistence of Sjögren's syndrome (SS) and Hashimoto thyroiditis (HT) has been confirmed, but the common mechanism of its co-occurrence remains unknown. This study aims to further explore the underlying mechanism and biomarkers for the co-occurrence of SS and HT. The Gene Expression Omnibus databases were used to obtain gene expression profiles for SS (GSE127952 and GSE23117) and HT (GSE29315 and GSE138198). ⋯ ROC analysis revealed that the 4 hub genes had a strong diagnostic value. Our study showed the common pathogenesis of SS and HT. These hub genes and diagnostic models may put forward some new insights for diagnosing and treating SS complicated with HT.
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The prognostic value of exercise capacity has been demonstrated in subjects with established cardiovascular diseases. We aim to evaluate the independence of exercise capacity measured by treadmill exercise test (TET) in predicting long-term outcomes among various comorbidities. This study was conducted from January 2003 to December 2012 in a tertiary medical center in Taiwan. ⋯ The fitness was more predictive of long-term outcomes in young or those with ischemic changes during TET (P for interaction: 0.035 and 0.018, respectively). The benefit of fitness was nonlinearly associated with long-term survival. The prognostic impacts of exercise capacity were universally observed in subjects with or without various comorbidities.
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This study aims to demonstrate current research priorities and predict future trends of sports medicine of athletes by scientometric analysis. We collected nearly 20 years (2003 to 2023) of publications related to Sports medicine of athletes in the Web of Science database, Citespace was applied to evaluate the knowledge mapping. There are 4820 manuscripts about post-cesarean section in total, and faster growth after 2018. ⋯ Through scientometric analysis of the past 20 years, we know the blood, biomedical imaging informatics, and activity monitor is the focus of future research. The USA, Australia, and England have become the main research forces in this field with high publication rates and centrality. This is important for accurately and quickly locating trends in this field.
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The aim of this study was to compare bioelectrical impedance analysis (BIA) with dual-energy X-ray absorptiometry (DXA) and investigate the accuracy of BIA in assessing appendicular skeletal muscle mass (ASM) and diagnosing sarcopenia. A total of 90 elderly patients hospitalized in the Affiliated Hospital of Hangzhou Normal University from 2019 to 2020 were collected, including 42 males and 48 females. ⋯ ASM measured by BIA was higher than ASM measured by DXA, and there was statistical significance for all differences (P < .001); Pearson correlation analysis showed that ASM measured by BIA and DXA was positively correlated in both male (R = 0.94) and female (R = 0.97) patients (P < .001); Bland-Altman analysis showed that there was a high consistency between ASM detected by BIA and DXA; The detection rate of low muscle mass and sarcopenia by BIA and DXA was not statistically significant (P > .05). BIA (InBody720) has high accuracy in assessing ASM and diagnosing sarcopenia in hospitalized Chinese older adults, and has the advantages of convenient use, no radiation, and easy promotion, so it can be used as an early screening tool in primary hospitals lacking DXA.
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Meta Analysis
The efficacy of different nimodipine administration route for treating subarachnoid hemorrhage: A network meta-analysis.
A systematic review and network meta-analysis (NMA) were conducted to explore the optimal administration route of nimodipine for treatment subarachnoid hemorrhage. ⋯ It is possible that both enteral and intravenous nimodipine have comparable effectiveness in preventing poor outcomes, DCI, and delayed ischemic neurological deficits. However, further investigation may be necessary to determine the exact role of intravenous nimodipine in current clinical practice.