Medicine
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This was a preliminary retrospective study to clarify the effectiveness of traditional Japanese acupuncture on the stress level of Japanese expatriates who studied or worked in Myanmar. Total 22 Japanese expatriate patients were selected for this study. The profile of mood states second edition-adult short form scale was used to evaluate the stress-relief effect of acupuncture before every treatment. ⋯ Regarding the influence of background, the experience of staying abroad significantly influenced the efficacy of the acupuncture treatment. These results indicate that acupuncture treatment can relieve stress experienced by Japanese expatriates. The results also suggest that the experience of staying abroad might be one of the leading factors that can modulate the effects of treatment.
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Observational Study
Attitudes toward herbal medicine for COVID-19 in healthcare workers: A cross-sectional observational study.
The coronavirus disease 2019 (COVID-19) pandemic has adversely affected working life all over the world, and the employees with the highest risk of transmission have been those in the health sector. Since there are currently no effective treatments for COVID-19, there have been numerous attempts to find alternative treatments for both the spread of the infection and its treatment. These efforts have included the use of herbal extracts to boost immunity and reduce the likelihood of contracting the infection. ⋯ The herb most frequently utilized was ginger (54%). Healthcare workers use HM at rates that are the same as those of the general population. Both its use during infections and the idea that it is effective are more common among healthcare professionals than in the general population.
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Observational Study
Platelet count predicts mortality in patients with sepsis: A retrospective observational study.
Platelet count is a key component of sepsis severity score. However, the predictive value of the platelet count at admission for mortality in sepsis remains unclear. We designed a retrospective observational study of patients with sepsis admitted to our hospital from January 2017 to September 2021 to explore the predictive value of platelet count at admission for mortality. ⋯ Multivariate logistic regression analysis indicated that age (P = .003), platelet count (P < .001) and lactate level (P = .018) were independent risk factors for mortality in patients with sepsis. Finally, the area under the receiver operating characteristic curve of platelet count predicting mortality in sepsis was 0.763 (95% confidence interval, 0.709-0.817, P < .001), with a sensitivity of 55.6% and a specificity of 91.8%. In our study, platelet count at admission as a single biomarker showed good predictability for mortality in patients with sepsis.
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We aim to investigate the mechanism and effective components of Shenghui decoction (SHD), which has been shown to inhibit acetylcholinesterase (AChE) through molecular docking (MD) and molecular dynamics simulation (MDS). The effective ingredients in SHD were collected through the TCMSP database and literature review. All components were docked with AChE using CDOCKER. ⋯ The binding energy of AChE and Tumulosic acid was -24.14 ± 2.46 kcal/mol. SHD contains many effective ingredients that may inhibit AChE activity. Tumulosic acid can occupy the binding site to prevent ACh from entering the chemical domain, thus exerting AChE inhibitory effect.
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Observational Study
Prolonged second stage of labor is associated with persistent urinary retention after forceps delivery: An observational study.
The occurrence of urinary retention is significantly higher in women undergoing forceps-assisted midwifery. However, the majority of these women typically regain the ability to urinate spontaneously within 72 hours after delivery. Instances of persistent urinary retention beyond this timeframe are relatively uncommon and have been rarely documented. ⋯ Univariate analysis revealed a significant difference in the duration of the second stage of labor between group A and group B. However, logistic regression analysis did not indicate any significant difference between the 2 groups. Further research is still required to determine whether the association between persistent urinary retention following forceps delivery and prolonged second stage of labor is significant, considering the limited number of cases available for analysis.