JAMA : the journal of the American Medical Association
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Cardiometabolic effects of second-generation antipsychotic medications are concerning but have not been sufficiently studied in pediatric and adolescent patients naive to antipsychotic medication. ⋯ First-time second-generation antipsychotic medication use was associated with significant weight gain with each medication. Metabolic changes varied among the 4 antipsychotic medications.
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Comparative Study
Comparison of physician workforce estimates and supply projections.
Estimates of physician supply in the United States have been based on data that may overestimate the number of older physicians in the workforce. ⋯ Compared with the Masterfile data, estimates using the CPS data found more young physicians entering the workforce and fewer older physicians remaining active, resulting in estimates of a smaller and younger physician workforce now and in the future.
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Recent studies indicate common etiologies for cardiovascular disease (CVD) and osteoporotic fractures. ⋯ A diagnosis of CVD was significantly associated with risk of subsequent hip fracture. Increased risks in co-twins without an index diagnosis suggest genetic factors in the association between CVD and osteoporotic fractures.