JAMA : the journal of the American Medical Association
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Randomized Controlled Trial Multicenter Study
Effect of 3 to 5 years of scheduled CEA and CT follow-up to detect recurrence of colorectal cancer: the FACS randomized clinical trial.
Intensive follow-up after surgery for colorectal cancer is common practice but is based on limited evidence. ⋯ Among patients who had undergone curative surgery for primary colorectal cancer, intensive imaging or CEA screening each provided an increased rate of surgical treatment of recurrence with curative intent compared with minimal follow-up; there was no advantage in combining CEA and CT. If there is a survival advantage to any strategy, it is likely to be small.
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Diverticulitis is a common disease. Recent changes in understanding its natural history have substantially modified treatment paradigms. ⋯ Recent studies demonstrate a lesser role for aggressive antibiotic or surgical intervention for chronic or recurrent diverticulitis than was previously thought necessary.