JAMA : the journal of the American Medical Association
The most recent articles from:
JAMA
2014
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Randomized Controlled Trial Multicenter Study
School-age outcomes of very preterm infants after antenatal treatment with magnesium sulfate vs placebo.
Antenatal magnesium sulfate given to pregnant women at imminent risk of very preterm delivery reduces the risk of cerebral palsy in early childhood, although its effects into school age have not been reported from randomized trials. ⋯ Magnesium sulfate given to pregnant women at imminent risk of birth before 30 weeks' gestation was not associated with neurological, cognitive, behavioral, growth, or functional outcomes in their children at school age, although a mortality advantage cannot be excluded. The lack of long-term benefit requires confirmation in additional studies.