JAMA : the journal of the American Medical Association
-
Review Practice Guideline Meta Analysis
Screening for Colorectal Cancer: Updated Evidence Report and Systematic Review for the US Preventive Services Task Force.
Colorectal cancer (CRC) remains a significant cause of morbidity and mortality in the United States. ⋯ Colonoscopy, flexible sigmoidoscopy, CTC, and stool tests have differing levels of evidence to support their use, ability to detect cancer and precursor lesions, and risk of serious adverse events in average-risk adults. Although CRC screening has a large body of supporting evidence, additional research is still needed.