JAMA : the journal of the American Medical Association
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Randomized Controlled Trial Comparative Study
Effect of Graded Sensorimotor Retraining on Pain Intensity in Patients With Chronic Low Back Pain: A Randomized Clinical Trial.
The effects of altered neural processing, defined as altering neural networks responsible for perceptions of pain and function, on chronic pain remains unclear. ⋯ In this randomized clinical trial conducted at a single center among patients with chronic low back pain, graded sensorimotor retraining, compared with a sham procedure and attention control, significantly improved pain intensity at 18 weeks. The improvements in pain intensity were small, and further research is needed to understand the generalizability of the findings.
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Care of adults at profit vs nonprofit dialysis facilities has been associated with lower access to transplant. Whether profit status is associated with transplant access for pediatric patients with end-stage kidney disease is unknown. ⋯ Among a cohort of pediatric patients receiving dialysis in the US from 2000 through 2018, profit facility status was associated with longer time to wait-listing and longer time to kidney transplant.
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This study describes reported interest in notification regarding use of personal health information and biospecimens for research and preference-associated factors among a sample of the US population in 2019.
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Comparative Study
Comparison of Strategies to Conserve Iodinated Intravascular Contrast Media for Computed Tomography During a Shortage.
This study models the amount of contrast that could be conserved in computed tomographic examinations in the context of the current global shortage of iodinated contrast media.
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Observational Study
Association Between Gout Flare and Subsequent Cardiovascular Events Among Patients With Gout.
Gout is associated with cardiovascular diseases. The temporal association between gout flares and cardiovascular events has not been investigated. ⋯ Among individuals with gout, those who experienced a cardiovascular event, compared with those who did not experience such an event, had significantly higher odds of a recent gout flare in the preceding days. These findings suggest gout flares are associated with a transient increase in cardiovascular events following the flare.