JAMA : the journal of the American Medical Association
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Randomized Controlled Trial Multicenter Study
Remote Ischemic Conditioning for Acute Stroke: The RESIST Randomized Clinical Trial.
Despite some promising preclinical and clinical data, it remains uncertain whether remote ischemic conditioning (RIC) with transient cycles of limb ischemia and reperfusion is an effective treatment for acute stroke. ⋯ RIC initiated in the prehospital setting and continued in the hospital did not significantly improve functional outcome at 90 days in patients with acute stroke.