JAMA : the journal of the American Medical Association
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JAMA
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Comment Pragmatic Clinical Trial
Screening for Helicobacter pylori to Prevent Gastric Cancer: A Pragmatic Randomized Clinical Trial.
Effects of screening for Helicobacter pylori on gastric cancer incidence and mortality are unknown. ⋯ Among residents of Taiwan, an invitation to test for HPSA combined with FIT did not reduce rates of gastric cancer or gastric cancer mortality, compared with an invitation for FIT alone. However, when differences in screening participation and length of follow-up were accounted for, gastric cancer incidence, but not gastric cancer mortality, was lower in the HSPA + FIT group, compared with FIT alone.