JAMA : the journal of the American Medical Association
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Cognitive decline is a major cause of disability in stroke survivors. The magnitude of survivors' cognitive changes after stroke is uncertain. ⋯ Incident stroke was associated with an acute decline in cognitive function and also accelerated and persistent cognitive decline over 6 years.
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The prevalence of cardiometabolic multimorbidity is increasing. ⋯ Mortality associated with a history of diabetes, stroke, or MI was similar for each condition. Because any combination of these conditions was associated with multiplicative mortality risk, life expectancy was substantially lower in people with multimorbidity.
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Comment
Long-term vs Short-term Therapy With Vitamin K Antagonists for Symptomatic Venous Thromboembolism.
Is long-term (≥3 months) vs short-term therapy with vitamin K antagonists (VKAs) associated with differences in the incidence of recurrent venous thromboembolism (VTE), major bleeding, and mortality in patients with symptomatic VTE? ⋯ Long-term treatment with VKAs is associated with a reduced risk for recurrent VTE and an increased risk for major bleeding compared with short-term treatment in patients with VTE, but is not associated with differences in mortality.