The Journal of family practice
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Case Reports
51-year-old woman • History of Graves disease • General fatigue, palpitations, and hand tremors • Dx?
► history of Graves disease ► general fatigue, palpitations, and hand tremors.
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NO. In general, nonoral estrogen use for menopausal symptoms is associated with a lower cardiovascular (CV) risk profile than oral estrogen use (strength of recommendation [SOR], B; meta-analysis of cohort studies). ⋯ Vaginal estrogen therapy also is associated with lower CV-related mortality for 3 to 5 years compared withnonuse (SOR, B; cohort study). No high-quality randomized trials address this topic.
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Multicenter Study
A new standard for treatment of torus fractures of the wrist?
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► myalgias and progressive symmetrical proximal weakness ► history of unilateral renal agenesis, type 2 diabetes, and hyperlipidemia.
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PROBABLY NOT. In patients who have hypertension, the timing of administration of antihypertensive medications does not appear to impact cardiovascular outcomes (strength of recommendation: B; contradictory randomized controlled trials).