Journal of the American Geriatrics Society
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To compare the predictive validity of the 2003 Beers, 2012 American Geriatrics Society (AGS) Beers, and Screening Tool of Older Persons' potentially inappropriate Prescriptions (STOPP) criteria. ⋯ All three criteria were modestly prognostic for ADEs, EDs, and hospitalizations, with the STOPP criteria slightly outperforming both Beers criteria. With low sensitivity, low specificity, and low agreement between the criteria, they can be used in a complementary fashion to enhance sensitivity in detecting ADEs.
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Multicenter Study
Infectious Disease-Related Emergency Department Visits of Elderly Adults in the United States, 2011-2012.
To investigate the frequency of infectious disease (ID)-related emergency department (ED) visits of elderly adults in the United States. ⋯ Using a nationally representative sample, it was found that the public health burden of IDs in elderly U.S. adults was substantial, as measured by ED visits, subsequent hospitalizations, and hospital-based mortality.
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Randomized Controlled Trial Multicenter Study
Prescription Opioids and Risk of Dementia or Cognitive Decline: A Prospective Cohort Study.
To determine whether prescription opioid use is associated with higher dementia risk or greater cognitive decline. ⋯ People with the heaviest opioid or NSAID use had slightly higher dementia risk than people with little or no use. These results may reflect an effect of chronic pain on cognition or residual confounding. Although opioids have other risks, little evidence of long-term cognitive harm specific to opioids was found.
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Multicenter Study
Pain in Community-Dwelling Older Adults with Dementia: Results from the National Health and Aging Trends Study.
To report prevalence, correlates, and medication management of pain in community-dwelling older adults with dementia. ⋯ Community-living older adults with dementia are at high risk of having pain. Creative interventions and programs are needed to manage pain adequately in this vulnerable population.
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Multicenter Study
Use of Medications with Anticholinergic Activity and Self-Reported Injurious Falls in Older Community-Dwelling Adults.
To assess the association between the use of medications with anticholinergic activity and the subsequent risk of injurious falls in older adults. ⋯ The regular use of medications with anticholinergic activity is associated with subsequent injurious falls in older men, although falls were self-reported after a 2-year recall and so may have been underreported. Further research is required to validate this finding in men and to consider the effect of duration and dose of anticholinergic medications.