Journal of the National Cancer Institute
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J. Natl. Cancer Inst. · Jul 2009
Meta AnalysisRacial disparities in cancer survival among randomized clinical trials patients of the Southwest Oncology Group.
Racial disparities in cancer outcomes have been observed in several malignancies. However, it is unclear if survival differences persist after adjusting for clinical, demographic, and treatment variables. Our objective was to determine whether racial disparities in survival exist among patients enrolled in consecutive trials conducted by the Southwest Oncology Group (SWOG). ⋯ African American patients with sex-specific cancers had worse survival than white patients, despite enrollment on phase III SWOG trials with uniform stage, treatment, and follow-up.
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J. Natl. Cancer Inst. · Jul 2009
Editorial CommentIs race really a negative prognostic factor for cancer?
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J. Natl. Cancer Inst. · Jul 2009
Comparative StudyLong-term outcomes among adult survivors of childhood central nervous system malignancies in the Childhood Cancer Survivor Study.
Adult survivors of childhood central nervous system (CNS) malignancies are at high risk for long-term morbidity and late mortality. However, patterns of late mortality, the long-term risks of subsequent neoplasms and debilitating medical conditions, and sociodemographic outcomes have not been comprehensively characterized for individual diagnostic and treatment groups. ⋯ Survivors of childhood CNS malignancies are at high risk for late mortality and for developing subsequent neoplasms and chronic medical conditions. Care providers should be informed of these risks so they can provide risk-directed care and develop screening guidelines.