Journal of the National Cancer Institute
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J. Natl. Cancer Inst.
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J. Natl. Cancer Inst. · Feb 2014
Multicenter StudyChemotherapy usage patterns in a US-wide cohort of patients with metastatic colorectal cancer.
Since the introduction of biologic therapies for the treatment of metastatic colorectal cancer (mCRC), few studies have examined patterns of care or predictors of specific treatment approaches. ⋯ Analysis of this US-wide mCRC cohort demonstrates that bevacizumab has been more consistently integrated into treatment regimens than anti-EGFR antibody therapies, particularly in first-line therapy. However, treatment choices vary substantially according to specific patient, practice, and provider characteristics.