Journal of neurosurgery
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Journal of neurosurgery · Jun 2015
Multicenter StudyGamma Knife radiosurgery for posterior fossa meningiomas: a multicenter study.
Posterior fossa meningiomas represent a common yet challenging clinical entity. They are often associated with neurovascular structures and adjacent to the brainstem. Resection can be undertaken for posterior fossa meningiomas, but residual or recurrent tumor is frequent. Stereotactic radiosurgery (SRS) has been used to treat meningiomas, and this study evaluates the outcome of this approach for those located in the posterior fossa. ⋯ Stereotactic radiosurgery affords a high rate of tumor control and neurological preservation for patients with posterior fossa meningiomas. Those with a smaller tumor volume and no prior radiation therapy were more likely to have a favorable response after radiosurgery. Rarely, additional procedures may be required for hydrocephalus or tumor progression.
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Journal of neurosurgery · Jun 2015
Case ReportsRemote transplantation of a third ventricle colloid cyst: case report.
The authors report the case of a 15-year-old girl with a third ventricle colloid cyst. She presented with prolonged headache, nausea, vomiting, and loss of visual acuity with bilateral papilledema. Computed tomography and MRI revealed severe biventricular hydrocephalus with transependymal periventricular fluid and a minimally enhancing cystic mass of the third ventricle. ⋯ While attempting to extricate the cyst from the patient's head, control of the cyst was lost and the cyst fell into the lateral ventricle beyond the surgeon's view. Postoperative imaging showed that the cyst had settled in the right occipital horn. After 3 years of follow-up, imaging suggests growth of the cyst in its new position without necrosis or displacement on prone imaging.
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Journal of neurosurgery · Jun 2015
Predictors of sinonasal quality of life and nasal morbidity after fully endoscopic transsphenoidal surgery.
Despite the increasing application of endoscopic transsphenoidal surgery for pituitary lesions, the prognostic factors that are associated with sinonasal quality of life (QOL) and nasal morbidity are not well understood. The authors examine the predictors of sinonasal QOL and nasal morbidity in patients undergoing fully endoscopic transsphenoidal surgery. ⋯ Sinonasal QOL following endoscopic pituitary surgery reaches a nadir at 2 weeks and recovers by 3 months postoperatively. Use of absorbable packing and nasal splints, while used in a minority of patients, negatively correlates with early sinonasal QOL. Sinonasal QOL and overall health status are well correlated in the postoperative period, suggesting the important influence of sinonasal QOL on the patient experience.
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Journal of neurosurgery · Jun 2015
Characteristics of Rathke's cleft cyst based on cyst location with a primary focus on recurrence after resection.
Rathke's cleft cysts (RCCs) are benign lesions with a location that is entirely intrasellar, intrasellar with suprasellar extension (intrasuprasellar), or purely suprasellar. The recurrence of RCC is relatively uncommon. The present study was conducted to report clinical characteristics, histological features, and outcomes based on location of the cyst with a primary focus on analyzing the predictors of squamous metaplasia and recurrence in these 3 types of RCCs. ⋯ A suprasellar cyst location, the occurrence of squamous metaplasia, and isointensity on T2-weighted MRI were independent predictors of RCC recurrence. The extent of resection and type of surgical approach used were not associated with recurrence. A tailored extent of resection based on cyst location and predictive factors is recommended.
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Journal of neurosurgery · Jun 2015
Case ReportsPallidal stimulation for Holmes tremor: clinical outcomes and single-unit recordings in 4 cases.
Holmes tremor (HT) is characterized by irregular, low-frequency (< 4.5 Hz) tremor occurring at rest, with posture, and with certain actions, often affecting proximal muscles. Previous reports have tended to highlight the use of thalamic deep brain stimulation (DBS) in cases of medication-refractory HT. In this study, the authors report the clinical outcome and analysis of single-unit recordings in patients with medication-refractory HT treated with globus pallidus internus (GPi) DBS. ⋯ The efficacy of GPi DBS exceeded that reported in prior studies of ventrolateral thalamus DBS and suggest GPi may be a better target for treating HT. These clinical and neurophysiological findings help illuminate evolving models of HT and highlight the importance of cerebellar-basal ganglia interactions.