Journal of neurosurgery
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Journal of neurosurgery · Jun 2015
Editorial CommentEditorial: Arteriovenous malformations and embolization.
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Journal of neurosurgery · Jun 2015
Editorial CommentEditorial: Turning fluorescence into black and white.
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Journal of neurosurgery · Jun 2015
Multicenter StudyStereotactic radiosurgery for intracranial hemangioblastomas: a retrospective international outcome study.
The purpose of this study was to evaluate the role of stereotactic radiosurgery (SRS) in the management of intracranial hemangioblastomas. ⋯ When either sporadic or VHL-associated tumors were observed to grow on serial imaging studies, SRS provided tumor control in 79%-92% of tumors.
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Journal of neurosurgery · Jun 2015
Review Case ReportsApoplexy of pituitary adenomas: the perfect storm.
Pituitary adenomas occasionally undergo infarction, apoplexy, which often destroys much of the tumor. It is well known that apoplexy can be precipitated by several acute factors, including cardiac surgery, other types of surgery, trauma, insulin infusion, and stimulation with administration of hypothalamic releasing factors. ⋯ The authors propose that the frequent ischemic infarction of pituitary adenomas is the product of intrinsic features of these tumors. These endogenous qualities create a tenuous balance between high metabolic demand and marginal tissue perfusion. Thus, the tumor is vulnerable to spontaneous infarction or to acute ischemia by any event that acutely alters the balance between tumor perfusion and tumor metabolism, events such as acute systemic hypotension, abruptly decreased supply of nutrients, hypoglycemia with insulin administration, or increase in the tumor's metabolic demand due to administration of hypothalamic releasing factors. It may be possible to take advantage of these intrinsic features of pituitary adenomas by using aspects of this vulnerability for development of new approaches for treatment.