European urology
-
Randomized Controlled Trial
Long-term intravesical adjuvant chemotherapy further reduces recurrence rate compared with short-term intravesical chemotherapy and short-term therapy with Bacillus Calmette-Guérin (BCG) in patients with non-muscle-invasive bladder carcinoma.
We present a randomised, parallel group, multicentre phase 4 trial comparing short- and long-term chemoprophylaxis with Mitomycin C (MMC) with short-term immunoprophylaxis with Bacillus Calmette-Guérin (BCG) after transurethral resection of the bladder for non-muscle-invasive bladder carcinoma. ⋯ Long-term MMC significantly reduced the risk of tumour recurrence without enhanced toxicity compared with both short-term BCG and MMC in patients with intermediate- and high-risk non-muscle-invasive bladder carcinoma. Our data provide a rationale for maintenance intravesical chemotherapy in this population.
-
To study the anatomical effects of placing a transobturator tape (TOT) in cadavers as well as determining the clinical outcome in men with urinary incontinence. ⋯ The TOT, a novel procedure for treatment of post-radical prostatectomy incontinence, was shown to be effective and well accepted by patients.
-
We present the case of a young female patient who developed a large subcapsular hepatic haematoma following extracorporeal shock wave lithotripsy (ESWL) administered to a stone in the right kidney. Severe haemorrhagic shock required a partial coiling embolisation of the right hepatic artery.
-
We investigated (1) whether sexual, physical, or emotional abuse experienced either as a child or as an adolescent/adult is associated with symptoms of urinary frequency, urgency, and nocturia, and (2) the extent to which the observed association between abuse and urologic symptoms may be causal. ⋯ Our analyses extend previous work. First, we show a strong association between abuse and urinary frequency, urgency, and nocturia in a community-based random sample. Second, we move beyond discussion of statistical association and find considerable evidence to suggest that the relationship between abuse and these symptoms may be causal.