European urology
The most recent articles from:
Eur. Urol.
-
Randomized Controlled Trial
Parenteral nutrition does not improve postoperative recovery from radical cystectomy: results of a prospective randomised trial.
After radical cystectomy, patients are in a catabolic state because of postoperative stress response, extensive wound healing, and ileus. ⋯ Postoperative TPN is associated with a higher incidence of complications, mainly infections, and higher costs following ePLND, cystectomy, and UD versus oral nutrition alone.
-
Randomized Controlled Trial Multicenter Study
A randomized, double-blind, dose-finding, multicenter, phase 2 study of radium chloride (Ra 223) in patients with bone metastases and castration-resistant prostate cancer.
Patients with castration-resistant prostate cancer (CRPC) and bone metastases have an unmet clinical need for effective treatments that improve quality of life and survival with a favorable safety profile. ⋯ Ra 223 had a dose-dependent effect on serum markers of CRPC activity, suggesting that control of bone disease with Ra 223 may affect cancer-related outcomes. Ra 223 was well tolerated at all doses.