The New England journal of medicine
The most recent articles from:
N. Engl. J. Med.
-
Comment Letter
Genetic variants in Lp(a) lipoprotein and coronary disease.
-
Randomized Controlled Trial Multicenter Study
Rifaximin treatment in hepatic encephalopathy.
Hepatic encephalopathy is a chronically debilitating complication of hepatic cirrhosis. The efficacy of rifaximin, a minimally absorbed antibiotic, is well documented in the treatment of acute hepatic encephalopathy, but its efficacy for prevention of the disease has not been established. ⋯ Over a 6-month period, treatment with rifaximin maintained remission from hepatic encephalopathy more effectively than did placebo. Rifaximin treatment also significantly reduced the risk of hospitalization involving hepatic encephalopathy. (ClinicalTrials.gov number, NCT00298038.)