The New England journal of medicine
The most recent articles from:
N. Engl. J. Med.
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Randomized Controlled Trial
Intensive insulin therapy in the medical ICU.
Intensive insulin therapy reduces morbidity and mortality in patients in surgical intensive care units (ICUs), but its role in patients in medical ICUs is unknown. ⋯ Intensive insulin therapy significantly reduced morbidity but not mortality among all patients in the medical ICU. Although the risk of subsequent death and disease was reduced in patients treated for three or more days, these patients could not be identified before therapy. Further studies are needed to confirm these preliminary data. (ClinicalTrials.gov number, NCT00115479.)
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Comment Historical Article
Adopting orphan drugs--two dozen years of treating rare diseases.