The New England journal of medicine
The most recent articles from:
N. Engl. J. Med.
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Comparative Study
Risk of death in elderly users of conventional vs. atypical antipsychotic medications.
Recently, the Food and Drug Administration (FDA) issued an advisory stating that atypical antipsychotic medications increase mortality among elderly patients. However, the advisory did not apply to conventional antipsychotic medications; the risk of death with these older agents is not known. ⋯ If confirmed, these results suggest that conventional antipsychotic medications are at least as likely as atypical agents to increase the risk of death among elderly persons and that conventional drugs should not be used to replace atypical agents discontinued in response to the FDA warning.