The New England journal of medicine
The most recent articles from:
N. Engl. J. Med.
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Randomized Controlled Trial Multicenter Study Clinical Trial
Long-term, low-intensity warfarin therapy for the prevention of recurrent venous thromboembolism.
Standard therapy to prevent recurrent venous thromboembolism includes 3 to 12 months of treatment with full-dose warfarin with a target international normalized ratio (INR) between 2.0 and 3.0. However, for long-term management, no therapeutic agent has shown an acceptable benefit-to-risk ratio. ⋯ Long-term, low-intensity warfarin therapy is a highly effective method of preventing recurrent venous thromboembolism.