The New England journal of medicine
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N. Engl. J. Med.
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Comment Randomized Controlled Trial Clinical Trial
The effect of fecal occult-blood screening on the incidence of colorectal cancer.
Both annual testing for fecal occult blood and biennial testing significantly reduce mortality from colorectal cancer. However, the effect of screening on the incidence of colorectal cancer remains uncertain, despite the diagnosis and removal of precancerous lesions in many persons who undergo screening. ⋯ The use of either annual or biennial fecal occult-blood testing significantly reduces the incidence of colorectal cancer.