The New England journal of medicine
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Randomized Controlled Trial Multicenter Study Clinical Trial
Amiodarone for resuscitation after out-of-hospital cardiac arrest due to ventricular fibrillation.
Whether antiarrhythmic drugs improve the rate of successful resuscitation after out-of-hospital cardiac arrest has not been determined in randomized clinical trials. ⋯ In patients with out-of-hospital cardiac arrest due to refractory ventricular arrhythmias, treatment with amiodarone resulted in a higher rate of survival to hospital admission. Whether this benefit extends to survival to discharge from the hospital merits further investigation.
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Letter Case Reports
Severe lung injury after exposure to chloramine gas from household cleaners.
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Randomized Controlled Trial Multicenter Study Clinical Trial
Increased mortality associated with growth hormone treatment in critically ill adults.
The administration of growth hormone can attenuate the catabolic response to injury, surgery, and sepsis. However, the effect of high doses of growth hormone on the length of stay in intensive care and in the hospital, the duration of mechanical ventilation, and the outcome in critically ill adults who are hospitalized for long periods is not known. ⋯ In patients with prolonged critical illness, high doses of growth hormone are associated with increased morbidity and mortality.