The New England journal of medicine
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Randomized Controlled Trial Multicenter Study Comparative Study Clinical Trial
Bortezomib or high-dose dexamethasone for relapsed multiple myeloma.
This study compared bortezomib with high-dose dexamethasone in patients with relapsed multiple myeloma who had received one to three previous therapies. ⋯ Bortezomib is superior to high-dose dexamethasone for the treatment of patients with multiple myeloma who have had a relapse after one to three previous therapies.
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Randomized Controlled Trial Multicenter Study Clinical Trial
Effect of treatment of gestational diabetes mellitus on pregnancy outcomes.
We conducted a randomized clinical trial to determine whether treatment of women with gestational diabetes mellitus reduced the risk of perinatal complications. ⋯ Treatment of gestational diabetes reduces serious perinatal morbidity and may also improve the woman's health-related quality of life.