The New England journal of medicine
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Randomized Controlled Trial
Dexamethasone in Vietnamese adolescents and adults with bacterial meningitis.
It is uncertain whether all adults with bacterial meningitis benefit from treatment with adjunctive dexamethasone. ⋯ Dexamethasone does not improve the outcome in all adolescents and adults with suspected bacterial meningitis; a beneficial effect appears to be confined to patients with microbiologically proven disease, including those who have received prior treatment with antibiotics. (Current Controlled Trials number, ISRCTN42986828 [controlled-trials.com] .).