The New England journal of medicine
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Retraction Of Publication
Retraction: Guo H. Complication of central venous catheterization. N Engl J Med 2007; 356: e2.
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Meta Analysis Comparative Study
Safety and efficacy of sirolimus- and paclitaxel-eluting coronary stents.
The safety of drug-eluting stents has been called into question by recent reports of increased stent thrombosis, myocardial infarction, and death. Such studies have been inconclusive because of their insufficient size, the use of historical controls, a limited duration of follow-up, and a lack of access to original source data. ⋯ Stent thrombosis after 1 year was more common with both sirolimus-eluting stents and paclitaxel-eluting stents than with bare-metal stents. Both drug-eluting stents were associated with a marked reduction in target-lesion revascularization. There were no significant differences in the cumulative rates of death or myocardial infarction at 4 years.
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Meta Analysis Comparative Study
Analysis of 14 trials comparing sirolimus-eluting stents with bare-metal stents.
The long-term effects of treatment with sirolimus-eluting stents, as compared with bare-metal stents, have not been established. ⋯ The use of sirolimus-eluting stents does not have a significant effect on overall long-term survival and survival free of myocardial infarction, as compared with bare-metal stents. There is a sustained reduction in the need for reintervention after the use of sirolimus-eluting stents. The risk of stent thrombosis is at least as great as that seen with bare-metal stents.