The New England journal of medicine
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Randomized Controlled Trial Multicenter Study Comparative Study
Long-term results of hypofractionated radiation therapy for breast cancer.
The optimal fractionation schedule for whole-breast irradiation after breast-conserving surgery is unknown. ⋯ Ten years after treatment, accelerated, hypofractionated whole-breast irradiation was not inferior to standard radiation treatment in women who had undergone breast-conserving surgery for invasive breast cancer with clear surgical margins and negative axillary nodes. (ClinicalTrials.gov number, NCT00156052.)