The New England journal of medicine
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Comment Letter
Prevention of leukemia relapse by donor activating KIR2DS1.
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Randomized Controlled Trial Multicenter Study
Hydroxyethyl starch or saline for fluid resuscitation in intensive care.
The safety and efficacy of hydroxyethyl starch (HES) for fluid resuscitation have not been fully evaluated, and adverse effects of HES on survival and renal function have been reported. ⋯ In patients in the ICU, there was no significant difference in 90-day mortality between patients resuscitated with 6% HES (130/0.4) or saline. However, more patients who received resuscitation with HES were treated with renal-replacement therapy. (Funded by the National Health and Medical Research Council of Australia and others; CHEST ClinicalTrials.gov number, NCT00935168.).