The New England journal of medicine
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Randomized Controlled Trial Multicenter Study
Biventricular pacing for atrioventricular block and systolic dysfunction.
Right ventricular pacing restores an adequate heart rate in patients with atrioventricular block, but high percentages of right ventricular apical pacing may promote left ventricular systolic dysfunction. We evaluated whether biventricular pacing might reduce mortality, morbidity, and adverse left ventricular remodeling in such patients. ⋯ Biventricular pacing was superior to conventional right ventricular pacing in patients with atrioventricular block and left ventricular systolic dysfunction with NYHA class I, II, or III heart failure. (Funded by Medtronic; BLOCK HF ClinicalTrials.gov number, NCT00267098.).
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Tracking national progress in diabetes care may aid in the evaluation of past efforts and identify residual gaps in care. ⋯ Although there were improvements in risk-factor control and adherence to preventive practices from 1999 to 2010, tobacco use remained high, and almost half of U.S. adults with diabetes did not meet the recommended goals for diabetes care.
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Editorial Comment
Gut microbiota, the genome, and diet in atherogenesis.