The New England journal of medicine
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Letter Historical Article
An Early American Smallpox Vaccine Based on Horsepox.
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Randomized Controlled Trial Multicenter Study Comparative Study
Romosozumab or Alendronate for Fracture Prevention in Women with Osteoporosis.
Romosozumab is a monoclonal antibody that binds to and inhibits sclerostin, increases bone formation, and decreases bone resorption. ⋯ In postmenopausal women with osteoporosis who were at high risk for fracture, romosozumab treatment for 12 months followed by alendronate resulted in a significantly lower risk of fracture than alendronate alone. (Funded by Amgen and others; ARCH ClinicalTrials.gov number, NCT01631214 .).