The New England journal of medicine
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Comment Randomized Controlled Trial Multicenter Study Comparative Study
Labor Induction versus Expectant Management in Low-Risk Nulliparous Women.
The perinatal and maternal consequences of induction of labor at 39 weeks among low-risk nulliparous women are uncertain. ⋯ Induction of labor at 39 weeks in low-risk nulliparous women did not result in a significantly lower frequency of a composite adverse perinatal outcome, but it did result in a significantly lower frequency of cesarean delivery. (Funded by the Eunice Kennedy Shriver National Institute of Child Health and Human Development; ARRIVE ClinicalTrials.gov number, NCT01990612 .).
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Randomized Controlled Trial Multicenter Study
Closed-Loop Insulin Delivery for Glycemic Control in Noncritical Care.
In patients with diabetes, hospitalization can complicate the achievement of recommended glycemic targets. There is increasing evidence that a closed-loop delivery system (artificial pancreas) can improve glucose control in patients with type 1 diabetes. We wanted to investigate whether a closed-loop system could also improve glycemic control in patients with type 2 diabetes who were receiving noncritical care. ⋯ Among inpatients with type 2 diabetes receiving noncritical care, the use of an automated, closed-loop insulin-delivery system resulted in significantly better glycemic control than conventional subcutaneous insulin therapy, without a higher risk of hypoglycemia. (Funded by Diabetes UK and others; ClinicalTrials.gov number, NCT01774565 .).
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Letter Case Reports
Anesthesia in a Patient with a Large Mediastinal Mass.