The New England journal of medicine
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Randomized Controlled Trial Multicenter Study Comparative Study
Six-Month Randomized, Multicenter Trial of Closed-Loop Control in Type 1 Diabetes.
Closed-loop systems that automate insulin delivery may improve glycemic outcomes in patients with type 1 diabetes. ⋯ In this 6-month trial involving patients with type 1 diabetes, the use of a closed-loop system was associated with a greater percentage of time spent in a target glycemic range than the use of a sensor-augmented insulin pump. (Funded by the National Institute of Diabetes and Digestive and Kidney Diseases; iDCL ClinicalTrials.gov number, NCT03563313.).