The New England journal of medicine
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Observational Study
Psychosis with Methylphenidate or Amphetamine in Patients with ADHD.
The prescription use of the stimulants methylphenidate and amphetamine for the treatment of attention deficit-hyperactivity disorder (ADHD) has been increasing. In 2007, the Food and Drug Administration mandated changes to drug labels for stimulants on the basis of findings of new-onset psychosis. Whether the risk of psychosis in adolescents and young adults with ADHD differs among various stimulants has not been extensively studied. ⋯ Among adolescents and young adults with ADHD who were receiving prescription stimulants, new-onset psychosis occurred in approximately 1 in 660 patients. Amphetamine use was associated with a greater risk of psychosis than methylphenidate. (Funded by the National Institute of Mental Health and others.).
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Letter Randomized Controlled Trial Comparative Study
Follow-up Computed Tomography after Evacuation of Chronic Subdural Hematoma.