The New England journal of medicine
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Editorial Comment
Baloxavir for Postexposure Prophylaxis against Influenza in Households.
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Letter Clinical Trial
Evidence for potential elimination of active Taenia solium transmission in Africa?
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Randomized Controlled Trial Multicenter Study
Vitamin D Supplements for Prevention of Tuberculosis Infection and Disease.
Vitamin D metabolites support innate immune responses to Mycobacterium tuberculosis. Data from phase 3, randomized, controlled trials of vitamin D supplementation to prevent tuberculosis infection are lacking. ⋯ Vitamin D supplementation did not result in a lower risk of tuberculosis infection, tuberculosis disease, or acute respiratory infection than placebo among vitamin D-deficient schoolchildren in Mongolia. (Funded by the National Institutes of Health; ClinicalTrials.gov number, NCT02276755.).
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Multicenter Study
Multisystem Inflammatory Syndrome in U.S. Children and Adolescents.
Understanding the epidemiology and clinical course of multisystem inflammatory syndrome in children (MIS-C) and its temporal association with coronavirus disease 2019 (Covid-19) is important, given the clinical and public health implications of the syndrome. ⋯ Multisystem inflammatory syndrome in children associated with SARS-CoV-2 led to serious and life-threatening illness in previously healthy children and adolescents. (Funded by the Centers for Disease Control and Prevention.).