The New England journal of medicine
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Letter Clinical Trial
Evidence for potential elimination of active Taenia solium transmission in Africa?
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Randomized Controlled Trial Multicenter Study
Baloxavir Marboxil for Prophylaxis against Influenza in Household Contacts.
Baloxavir marboxil (baloxavir) is a polymerase acidic protein (PA) endonuclease inhibitor with clinical efficacy in the treatment of uncomplicated influenza, including in outpatients at increased risk for complications. The postexposure prophylactic efficacy of baloxavir in the household setting is unclear. ⋯ Single-dose baloxavir showed significant postexposure prophylactic efficacy in preventing influenza in household contacts of patients with influenza. (Funded by Shionogi; Japan Primary Registries Network number, JapicCTI-184180.).