The New England journal of medicine
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Comparative Study
A Bivalent Omicron-Containing Booster Vaccine against Covid-19.
The safety and immunogenicity of the bivalent omicron-containing mRNA-1273.214 booster vaccine are not known. ⋯ The bivalent omicron-containing vaccine mRNA-1273.214 elicited neutralizing antibody responses against omicron that were superior to those with mRNA-1273, without evident safety concerns. (Funded by Moderna; ClinicalTrials.gov number, NCT04927065.).