The New England journal of medicine
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New approaches for the prevention and elimination of malaria, a leading cause of illness and death among infants and young children globally, are needed. ⋯ In this small trial, L9LS administered intravenously or subcutaneously protected recipients against malaria after controlled infection, without evident safety concerns. (Funded by the National Institute of Allergy and Infectious Diseases; VRC 614 ClinicalTrials.gov number, NCT05019729.).