The New England journal of medicine
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Randomized Controlled Trial Multicenter Study Comparative Study Pragmatic Clinical Trial
Collagenase Injection versus Limited Fasciectomy for Dupuytren's Contracture.
Treatments for Dupuytren's contracture include limited fasciectomy and collagenase injection. Comparisons of the effectiveness of these treatments have been limited. ⋯ Collagenase injection was not noninferior to limited fasciectomy with respect to the score on the PEM at 1 year after treatment. (Funded by the National Institute for Health and Care Research Health Technology Assessment Programme; DISC ISRCTN Registry number ISRCTN18254597.).