International journal of radiation oncology, biology, physics
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Int. J. Radiat. Oncol. Biol. Phys. · Sep 1995
Clinical TrialLow doses of prophylactic cranial irradiation effective in limited stage small cell carcinoma of the lung.
Prophylactic cranial irradiation (PCI) for the prevention of brain metastasis in small cell lung cancer remains controversial, both in terms of efficacy and the optimal dose-fractionation scheme. We performed this study to evaluate the efficacy of PCI at low doses. ⋯ In this patient population, relatively low doses of PCI have accomplished a significant reduction in the incidence of brain metastasis with little toxicity. Whether such treatment truly improves survival awaits the results of additional prospective randomized trials.
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Int. J. Radiat. Oncol. Biol. Phys. · Sep 1995
Base-of-tongue carcinoma: treatment results using concomitant boost radiotherapy.
To evaluate the efficacy of accelerated fractionated radiotherapy using the concomitant boost schedule for patients with squamous cell carcinoma of the base of tongue. ⋯ The concomitant boost fractionation schedule is a very effective regimen for this disease when appropriately selected patients are treated with meticulous technique. The therapeutic ratio is favorable, with a high rate of disease control and no persistent severe late complications. Patients whose neck disease responds completely to treatment with this schedule do not appear to need a planned neck dissection.
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Int. J. Radiat. Oncol. Biol. Phys. · Sep 1995
The role of radiotherapy in the management of spinal cord glioma.
To determine the role of radiotherapy in the management of spinal cord gliomas. ⋯ Postoperative conventional radiotherapy is indicated after less than total resection of low-grade ependymal tumors and astrocytomas but not after total resection of ependymomas. Radiocordectomy may be an option for certain cases with high-grade astrocytic tumors.