International journal of radiation oncology, biology, physics
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Int. J. Radiat. Oncol. Biol. Phys. · Oct 1998
Comparative StudyProstate cancer in African-American men: outcome following radiation therapy with or without adjuvant androgen ablation.
To compare the outcome of irradiated clinically localized prostate cancer in African-American and white patients. ⋯ Although African-American patients tend to have higher pretreatment PSA levels than white patients, the outcome for the disease is similar in the two groups when stratified by known pretreatment prognostic factors. Our data provide no evidence for the hypothesis that prostate cancer in African-Americans is intrinsically more virulent than in whites.
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Int. J. Radiat. Oncol. Biol. Phys. · Oct 1998
Late effects of intraoperative radiation therapy in anastomotic rat colon.
to determine whether intraoperative radiotherapy causes long-term negative effects on the healing of colonic anastomoses in the rat. ⋯ Intraoperative irradiation with a single dose of 10-20 Gy, delivered to the distal limb used for anastomotic construction, does not appear to constitute a threat to anastomotic integrity. Dose-related changes included formation of adenocarcinomas and fibrosis, but function and histology of the anastomosis proper remained unaffected.