International journal of radiation oncology, biology, physics
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Int. J. Radiat. Oncol. Biol. Phys. · Sep 2010
A population-based study of subsequent primary malignancies after endometrial cancer: genetic, environmental, and treatment-related associations.
To examine the risk of subsequent primary malignancies (SPMs) in women diagnosed with endometrial cancer. ⋯ Genetic, environmental, and treatment-related factors influence SPM risk. Genetic factors may contribute to the increased risk of colorectal cancer. Smoking's negative effect on endometrial cancer risk factors might explain the decreased risk of lung and oropharyngeal cancer. Patients treated with radiotherapy likely have a small but significantly increased risk of bladder, vagina, colon, and soft-tissue SPM.
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Int. J. Radiat. Oncol. Biol. Phys. · Sep 2010
Case ReportsIntegration of functional MRI and white matter tractography in stereotactic radiosurgery clinical practice.
To study the efficacy of the integration of functional magnetic resonance imaging (fMRI) and diffusion tensor imaging tractography data into stereotactic radiosurgery clinical practice. ⋯ Functional structures and fiber tracts could receive high doses if they were not considered during treatment planning. With the aid of fMRI and tractography images, they can be delineated and spared.
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Int. J. Radiat. Oncol. Biol. Phys. · Sep 2010
Hypofractionated boost to the dominant tumor region with intensity modulated stereotactic radiotherapy for prostate cancer: a sequential dose escalation pilot study.
To evaluate the feasibility, tolerability, and preliminary outcomes in patients with prostate cancer treated according to a hypofractionated dose escalation protocol to boost the dominant tumor-bearing region of the prostate. ⋯ Intensity-modulated radiotherapy hypofractionated boost dose escalation under stereotactic conditions was feasible, and showed excellent outcomes with acceptable long-term toxicity. This approach may well be considered an alternative to high-dose-rate brachytherapy.
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Int. J. Radiat. Oncol. Biol. Phys. · Sep 2010
Comment LetterThe rate of secondary malignancies after radical prostatectomy versus external beam radiation therapy for localized prostate cancer: a population-based study on 17,845 patients. In regard to Bhojani et al. (Int J Radiat Oncol Biol Phys 2010;76:342-348.).