Clinical nuclear medicine
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Clinical nuclear medicine · Sep 1993
Case ReportsHiatal hernia on whole-body radioiodine survey mimicking metastatic thyroid cancer.
Total body I-131 scanning done on a 67-year-old woman with thyroid cancer revealed abnormal tracer uptake within the mid-thorax, thought to represent metastasis in the mediastinum or thoracic spine. Single-photon emission computed tomography images of the thorax showed contiguity between the thoracic uptake and the normal, physiologic uptake of radioiodine in the stomach, suggesting physiologic accumulation within a hiatal hernia. ⋯ A hiatal hernia was also observed as an incidental finding on chest radiographs and an MRI. This case illustrates the potential for an abnormal anatomic configuration to mimic metastatic thyroid cancer and shows how SPECT and oral Tc-99m SC images may be useful in making this distinction.
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Clinical nuclear medicine · May 1993
Comparative Study Clinical TrialPhase II study of Tc-99m MAG3 in patients with nephrourologic diseases.
Tc-99m-labeled mercaptoacetyltriglycine (Tc-99m MAG3) is a recently introduced radioagent that is excreted by tubular function. The aim of this study was to test Tc-99m MAG3 as an imaging agent for renal scintigraphy and renal plasma flow measurement. Image quality was tested with four different administered doses of Tc-99m MAG3, 100 MBq, 200 MBq, 300 MBq and 400 MBq, in four patients each. ⋯ The mean labeling yield of Tc-99m MAG3 was 97%. None of the patients complained of side effects from Tc-99m MAG3. Tc-99m MAG3 is concluded to have good properties as a tubular radioagent for dynamic renal scintigraphy and renal plasma flow measurement.