Intensive care medicine
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Intensive care medicine · Jan 1993
The effects of norepinephrine on hemodynamics and renal function in severe septic shock states.
To investigate the effect of norepinephrine (NE) on hemodynamics, oxygen metabolism and renal function in patients with severe septic shock. ⋯ Our results suggest that norepinephrine can be used safely in the treatment of severe septic shock states. Mean arterial pressure and glomerular filtration rate improved markedly without deleterious effects on CI, O2AVI and VO2I.
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Intensive care medicine · Jan 1993
Clinical TrialRight ventricular function in early septic shock states.
To define a variable which could reliably predict when fluid resuscitation as monotherapy is not expected to improve organ perfusion pressure, owing to limitations in cardiac output responsiveness in patients with severe sepsis. ⋯ In 27 septic shock patients investigated, we diagnosed right ventricular dysfunction in 41%. In this specific patient population fluid replacement alone did not succeed in stabilizing hemodynamic variables, therefore necessitating catecholamine therapy.
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Intensive care medicine · Jan 1993
Inspiratory pressure/maximal inspiratory pressure ratio: a predictive index of weaning outcome.
To compare the accuracy of PI/PImax ratio and other commonly used indices in predicting weaning outcome. ⋯ The PI/PImax ratio provided a good separation between the patients who were successfully weaned and those who failed. It provides additional discriminative power to f/VT.
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Intensive care medicine · Jan 1993
Retracted PublicationDoes platelet size correlate with function in patients undergoing cardiac surgery?
Platelet dysfunction secondary to cardiopulmonary bypass (CPB) is one of the major reasons for nonsurgical post-operative bleeding in cardiac surgery. Whether platelet size is an indicator for platelet function was investigated in patients undergoing coronary artery bypass grafting. ⋯ Platelet volume is easy to measure even in the operation room or in ICU and may indicate abnormalities in platelet function in the post-bypass period of cardiac surgery patients.